I upgraded to 1.22 when it came out, and installed Spam Karma a couple of days ago.
Just now, a user on AOL who's been vacationing for a week tried to leave a comment, and couldn't, and mentioned it was her AOL browser preventing her suddenly (she's commented lots previously). I loosened up Spam Karma a bit, to "lenient," and am having her give it another shot.
She wasn't more specific as to error messages or anything... Any ideas what might have caused this? Or how to fix?