How to dynamically change content from a list with/without frames

So I have a page where I have a list of items. Each item is clickable to show more information about the topic. However, instead of using anchors, I would like it to open beside the list. So if I click item 1, then next to the list, the information is displayed. If I click item 2, then the information for item 1 is replaced with the information from item 2. I have been trying to use frames but even in the HTML(text) editor, my page only displays white space unless I use inline frames. I am not so fond of that because along with the information, I would like a picture to change with each click as well. Any ideas or help is most appreciated.

Thanks.