How to Deactivate Post Layout in Write options - Post
What is this for a question, what is the goal?
But if the plugin have a Meta box or widget, then update settings of Adminimize and add a custom rule for the ID or class of the addional areas of your plugin. After your save this setting you can active for hide for different roles.
HOW TO FIND custom rule for the ID or class
You must log in to post.