I am not too familier with scripts and wordpress3.0.1 Multi Sites' But I shall, try
With wp-3.0.1 multi Sits, sub domains are created via the parent wordpress domain
But what if you have a custom built or pre-formated wordpress site that comes with it's own: image file, wp-content and wp-config.php file.php file
You can't upload it as a theme and you can't alter the parent
wp-config.php file in the root file!
I have tried creating an individial folder, and seperate MySQL data base (updating the wp-config.php file) and uploading everthing to this folder.
But cannot access this from the back end/Dashboard of the multi site sub domain
Hope this makes a little more sence
Or should I just forget about aquireing pre-foremated Nich wordpress sites?