I'm running a large MultiSite installation, and this plugin is perfect for containing what my users can see & do, as well as providing them with instructions/info via the custom dashboard.
The import/export feature is great, as it allows me to store a set of options, then apply it to one of my subsites. This could be improved, however, by allowing me to mass-apply settings to multiple sites... right now I have to do it one-by-one, which is tedious even with the import settings feature.
There also seems to be an issue where, even if I have excluded them from seeing their Profile, they can still get to and edit it (by directly entering an excluded wp-admin/xxx URL, or clicking on an add-on or menu item that they can't modify (these redirect to the Profile). Many plugins of this type have the same problem, so it must be difficult to circumvent, but I'm surprised one can't simply block the body of the Profile page from displaying.
All-in-all, a very excellent and useful plugin!