I've been hard at work on BackUpWordPress 2.0 and it's nearly ready, before I release it however I would love to get some beta testers using it to make sure I haven't missed any major bugs.
The main new features of 2.0 are
- Full support for multiple schedules
- Power new interface for managing excludes
- More robust core backups engine
Under the hood it's a pretty large re-write.
To help out with testing you just need to download the development version from here http://downloads.wordpress.org/plugin/backupwordpress.zip
The unzip it and upload it to your site replacing the existing version of backupwordpress.