I'm running successfully wordpress out of its own directory under my root, http://www.example.com/wordpress/.
The actual site URL is http://www.example.com. And this is working.
However, I've had to insert the directory in front of my permalinks to make them work i.e.
I know that index.php can be removed by modifying the .htaccess file. Is it possible to remove /wordpress/ from the URL in the same way? If so, how? :-)