With the mightyseek forums down, I thought i'd try to gather podpress issues, links to fixes and other efforts here.
I'm currently trying to pursue the issue that in IE7 with WYSIWYG editing on you can't actually get to edit or start a new post. this seems to be down to the code in podpress.js "refPlayerDiv.innerHTML=[etc]"
which is triggering this issue http://support.microsoft.com/default.aspx/kb/927917 i'll post back if i get any further on this.
feel free to post/link to known 8.8 issues here - it would be nice to have a central resource.
small tip: in WP2.5+, comment out all of podpress_admin_postedit.js - it's code for the old admin interface (new dbxGroup etc), that just causes JS errors now.