Verify the integrity of a WP installation by scanning for unexpected or modified files.
The plugin is only meant to be used with single-site WordPress installations. Some features may still work under multi-site environments, however it would be safer to use some other plugin that is specifically marked WPMU-compatible instead.
No, Look-See merely points out any irregularities it finds. It is left to you to manually review any affected files to determine whether or not they pose a threat.
We generally have a new file database ready to go within 24 hours of a new WordPress release (we're nerds).
Take a look at your FTP program's settings and change the transfer type from ASCII (or automatic) to Binary. If your program doesn't support this, try FileZilla: http://filezilla-project.org/.
Not necessarily. There could still be backdoors elsewhere on the server. As always, we recommend you maintain best security practices and keep regular back-ups.
Don't count on it. As a general rule, you should always be running the latest version of WordPress anyway. Not doing so is not safe.
Not yet, sorry. Automated scans will probably be integrated into a future release, so stay tuned!