I think it would be great to have the ability upon installation to change the folder names and locations for WP files. This would permit a greater amount of security for WP installations.
For example, if I wanted to rename the "wp-admin" folder to "site-admin", then I would have the ability to do so. I would think this could be something added to the database and maybe a mod to the htaccess file like we already do using permalinks.
Currently, we can move the uploads file, and the wp-config file. However, if we could rename these, we provide more security in doing so.