I kvetched on this, too, just so it's captured, but...
Right now, when you're drafting a WordPress post in WP 2.5.1, the "Save" and "Publish" buttons are right next to each other.
It's generally a bad thing in user interface heuristics to put a destructive or non-undoable action (such as delete document, publish blog entry, send e-mail, etc.) right next to a button that you access frequently and often automatically (like "Save").
In WordPress, this makes it easy to publish a half-finished post when you're really trying to click "Save."
"Preview" would make a much better pairing with "Save" since you frequently will save before previewing. Regardless, it would be smart to move "Publish" away from "Save." Save us all the embarrassment of publishing half finished posts that get cached or picked up via RSS immediately.
This problem breaks two UI principles:
1) Present a design which prevents problems from occurring (via error-prone conditions) [Problem: Save/Publish too close together]
2) If you can't do the above, give users a confirmation option before they commit to an option. [Problem: No user confirmation option before WordPress Publish]
Gotta fix one of these (or both)...